Abstract:
This study was conducted for serological detection of Helicobacter pylori antibodies in serum
of diabetic patients and non diabetic individuals in Khartoum State during the period April to
September 2022. Blood samples were collected from 180 individuals ( 120 diabetic patients
and 60 non diabetic patients ),Two milliliters of blood sample was collected in plain
containers from each diabetic patient and non diabetic patient and let it until clot and serum
was separated used centrifuge and tested for the presence of Helicobacter pylori IgG
antibodies using rapid test device(ECO test). Helicobacter pylori IgG antibodies were
detected in 35 (58.3%) of the diabetic patients that treated with insulin total of 60 patients,
and detected in 39 (65%) of the diabetic patients treated with anti diabetic agent total of 60
patients , in the non diabetic individual were detected in 27 (45%) positive total of 60 non
diabetic individuals, It was in agreement with other studies,in (Vafaeimanesh et al.,2015)
found that the prevalence of HP seropositive was (65.9%) versus (50.5%) in diabetic and non
diabetics, respectively, and the difference was statistically significant, this result is close to
present study, (Jamshid et al.,2014) found that the prevalence of Helicobacter
pylori infection was (55.8%) in diabetics and (44.2%) in non diabetics ,(Roussos and
Angeliki ,2002) reported that the prevalence of H. pylori between diabetics (37.3%) and non
diabetics (35.2%) .The high frequency of positive subject among diabetic treated with anti
diabetic agent 39 (65%) and the correlation was statistically not significant more than
(P<0.05).And detection of Helicobacter pylori should be routine in diabetic patient and
further studies in diabetic mainly those treated with antidiabetic agent.
