Isolation, Identification and A ntimicrobial Sensitivity of Common Bacteria in Different Clinical Specimens from Cancer Patients under Chemotherapy in Shendi City- Sudan.

Abstract

Patients with cancer are highly susceptible to almost any type of bacterial infection. This cross sectional descriptive study(February to May 2022) was aimed to isolate common bacteria in patients under chemotherapeutic drug. Isolation of bacteria and their antibiotic sensitivity were made by cyctine lactose electerolyte deficient agar (CLED) , biochemical media, muller Hinton agar and single disk of antibiotic. Out of 100 samples(urine ,swab) that collected from patients under chemotherapeutic drug were found 10 types of bacteria. Of 70 urine sample 46(65.7%) show growth, while 24(34.3%) show no growth and 30 swabs samples, 23(76.7%) show growth while 7(23.3%) show no growth, the distribution of isolated organism were klebsiellappneumoniae(Kpneumonia)15(32.6%),Escherichiacoli(E.coli)9(19.6%), proteus mirabilis(P.mirabilis)7(15.2%), proteus vulgaris(P.vulgaris) 6(13%), Staphylococcus.aureus (S.aureus) 7(15.2%) and citrobacterfreundii (C.freundii)2(4.3%)pseudomonas.aeurginosa(Ps aeurginosa). 3 (13%), Streptococcus pyogens (S.pyogens) 2 (8.7%), Enterococcus faecalis (E faecalis)3(13%), Streptococcus. pneumoniae 1 (0.1%). Total of 69 sample show growth in males constitutes 30(43.5%) while female constitutes 39(56.5%), there was statically significant association between gender and bacterial growth (P value 0.05 ), and no statically significant association between age and bacterial growth (P value 0.09 ). The most sensitive antibiotic areimpenem and ciprofloxacin and resistant are ciftazidimcefexime and ceftriaxone.