Assessment of plasma Calcium and Phosphorus Levels of Sudanese Pregnant Women in Khartoum state

Abstract

This is a case control study conducted in Soba University Hospital during period from august to Octobers 2014 . The aim of this study is compare plasma calcium and plasma phosphate between pregnant women in different stages of pregnancy and healthy non pregnant women. Sixty blood samples were collected from healthy Sudanese pregnant women and divided into first , second , and third trimester as test group and twenty health non pregnant women as control group. Plasma calcium and phosphorus were measured by auto analyzer called cobas its fully automation, then data were analyzed by statistical (SPSS) software . The study showed insignificant decrease in plasma calcium levels when compared test group (9.02±0.47mg/dl) with control (9.35±0.75mg/dl) (p.value 0.137) , and significant reduction when compare first with third trimester ( p.value 0.000). No significant change in plasma phosphorus levels in tests group (3.32±0.51 mg/dl) compared with mean of control group (3.59±0.65 mg/dl) (p.value 0.064). insignificant weak positive correlation between phosphorus and calcium ( p.value 0.226) (r=0.137). measurement of serum calcium should be done regularly during pregnancy and pregnant women should take diet rich with calcium or calcium supplement which is needed to compensate increase demand of fetus .