The Effects of Diabetes Milletus Type-II on the Complete Blood Count among Sudanese patients- Khartoum State

Abstract

Diabetes mellitus is currently emerging as an important health problem in Sudan, especially in urban areas; which also affect the blood cells parameters in different ways in which may play a role in development of complications in diabetic patients. This was a cross sectional study done in ALshaheeda Nada Health Center in Al Haj Yousif neighborhood in the period between February 2017 and March 2017, aimed to study the CBC parameters in patients with diabetes mellitus type II, designed and to determine the effect of DM type II on CBC parameters. One hundred fifty subjects were recruited for this study, 100 patients with DM type II patients and 50 healthy volunteers as a control group, blood samples were collected from all participants in EDTA vacutainers tubes. Patients' data were collected by structured interview questionnaire and analyzedby statistical package for social sciences (SPSS), version 16. Complete blood count parameters were measured by automated hematologyanalyzer (Sysmex XE_2100). There was statistically significant decrease in hemoglobin concentration, MCV, MCH and MCHC (P.value =0.00, 0.02, 0.01, 0.00 respectively) and no statistically significantchange in RBCs and HCT (P.value = 0.34 and 0.34 respectively) in DM type II patients when compared with healthy controls. There was statistically significant increased in MXD count (P. value =0.04) with no statistically significant difference in platelets, WBCs, lymphocytes and neutrophil counts (P. value = 0.57, 0.09, 0.99, 0.51 respectively) when compared with healthy control. This study conclude that CBC parameters HB, MCV, MCH, MCHC and Mixed count were significantly lower among diabetic subjects compared to apparently healthy controls and no significant difference on the other parameters namely RBC, WBC, PLT and HCT.