A comparison of two intramascular doses of Xylazine- Ketamine combination in Sudanese dogs

Abstract

The purpose of this study was to determine the effects of Safe and effective aneasthesia of different protocols of Xylazine-Ketamine on clinical and anaesthesia parameters in attempts to produce safe and satisfactory total intramascular anaesthesia in dogs(10 local breed dogs were used in this study 5dogs for each group).. In this study two protocols were used: Protocol Xylazine 1mg/kgketamine 15mg/kg i/m for group 1 and Protocol Xylazine 1.5 mg/kgketamine 15mg/kg i/m for group 2 All anaesthitic protocols produced satisfactory induction and rapid smooth recovery and there were significant increase in the duration of anaesthesia during protocol two compared to protocol one . In the duration of lateral recombency, sterna recombenc, standing position and total recovery time was monitoring during course of anaesthesia. induction of anaesthesia, muscle relaxation and recoveries were satisfactory in both protocols used. The clinical and anaesthetic parameters were measure before, during and after anesthesia at interval 10, 20, 30,40,50,60 minutes throughout the duration of the experiment. The heart and respiratory rates were significantly depressed (p<0.05) value of 86.40±33.54 beat /minutes (group1), 120.40±25.74 beat /minutes (group2) 86.40±33.54 beat /minutes (group1), 120.40±25.74 beat /minutes (group2) twenty minutes post induction of aneasthetic protocol and 86±33.97 beat /minutes (group1) and 120±22.14 beat /minutes (group2) fifty minutes post induction of the aneasthetic protocol. The respiratory was 14±4.85 breath/ minute (group1) and 16.80±5.40 breath/ minute (group2) ten minutes post induction of aneasthetic protocol. Moderate aneasthesia and muscle relaxation was evident into the aneasthesia 1.60±0.89 minutes (group1) and 2±0 minutes (group2). Postoperative care was given to body temperature, degree of sedation and appropriate analgesia. All reflexes disappeared 54±8.94Minutes (group1) and 56±11.40Minutes (group2). It is concluded that both protocols didn‟t cause any harmful effect to both cardio pulmonary systems therefore, both protocols can be used in the local breed dogs and they proof to be efficient with good analgesia and good muscle relaxation, and with wide margin of safety.