Correlation of thyroid uptake and function test

Abstract

The main objective of the present work was to study the relationship between thyroid function test and thyroid uptake using 99mTc. The study was also designed to help in determining the normal range of the thyroid uptake in Sudanese people as well as the possibility of using thyroid uptake with accuracy similar to the TFT. This study includes 77 patients in different age, sex, center of origin and type of food and drink intake. The study was conducted at RICK; nuclear medicine department (gamma camera and RIA) for five months From MAY to SEP 2009. the levels of thyroid hormones T4, T3, TSH and thyroid uptake are (5.6±3.6, 79.8±6.5, 6.7±0.8 and 6.3±2.4 respectively), in the subject’s blood were measured using sensitive RIA method against the thyroid uptake value in the gamma camera (mediso).the result of this study showed that, there was a direct relationship between thyroid uptake and the level of the thyroid related hormones (for individual). There is strong and significant correlation at p = 0.05 between the thyroid uptake versus T3 and T4.The percentage of thyroid uptake for the subjects included in the study was ranging between 5.78 and 6.12. Also the study indicated that there were possibilities of using thyroid uptake only as a diagnostic tool for thyroid activity without TFT due to the ability of thyroid uptake to giving sufficient information concerning thyroid status.