Association between Lipids and Metabolic Syndrome Components among Metabolic Syndrome Patients

Abstract

Metabolic syndrome (MetS) associates with higher morbidity and mortality. This study aimed to correlate between lipids and metabolic syndrome components among MetS patients. This case control study included 215 metabolic syndrome patients and 215 apparently healthy individuals.The demographic data, waist circumference (WC) and blood pressure (BP) were obtained; fasting blood glucose (FBG) and lipid profile were measured by Mindray automated analyzer, small dense low-density lipoprotein (sdLDL) was measured by ELISA. The associations between lipids and metabolic syndrome components were investigated by Pearson’s correlation test of SPSS version 21. Compared to control group, FBG, cholesterol, triglycerides, and LDL-C levels were significantly increased with p.value (0.000, 0.000, 0.000 and 0.000 respectively) whereas HDL-C was reduced p.value (0.000), while no difference was found in sd-LDL level with p.value (0.209). The mean body mass index (BMI) in females was significantly higher than males with p-value (0.016), systolic BP was positively associated with BMI, FBG, WC, cholesterol and LDL-C with p-value (0.009, 0.000,0.002, 0.000 and 0.006 respectively) whereas LDL-C was positively associated with FBG with p-value(0.014). MetS patients had elevated triglycerides, cholesterol, LDL-C, and reduced HDL-C. Lipids were found potentially associated with MetS components.