Serum GGT and ALT Level in Sudanese Diabetic Patients Type Two

Abstract

The present study examined the effect of Diabetes mellitus type 2 on GGT and ALT in diabetic patients. This cross-sectional study comprised of fifty diabetic patients; of those patients, 25 were females (aged 30_60 years) and 25 were males (aged 30_60 years) Also, 20 Volunteers non diabetic (apparently healthy) were involved as a control in this study; 10 were females (aged 30_60 years) and 10 were males (aged 30_60 years).. Subject selection was done by a non-random (non-probability) sampling procedure from the diabetic patients in the Friendship Hospital in Khartoum state during period of (April to July/2010). Serum levels of GGT and serum ALT was performed manually by using enzymatic reaction depended reagents. The serum levels of GGT and serum ALT showed significant increase in diabetic patients compared to the control group (P.Value ≤ 0.05). Means ± SD of serum liver enzymes for diabetic’s patients versus controls: (1.40 ± 0.81) U/L versus (1.00 ± 0.00); for serum ALT (U/L). (2.64 ± 0.78) U/L versus (1.00 ± 0.00); for Serum GGT (U/L). The present study, revealed significant increase in serum levels of GGT and serum ALT in diabetic patients type 2 probably due to the duration of Diabetes Type 2 (4-6 years) and the age of diabetic Type 2 patients (30-60) in our study.