Evaluation of uterine blood flow in recurrent pregnancy loss by using color Doppler

Abstract

The pregnancy loss was one of the major problems facing the pregnant women in the first trimester. Knowing the causes or the characteristics of the abortion will help in improve the result. The general objective of this study was to evaluate the uterine artery blood flow indices (PI, RI and PSV) of RPL. The data were collected from 600 patients where 300 were study group and 300 as control group. The study group were consisted of three categories; threaten abortion, elective abortion and non pregnant, each of them consisted of 100 patients and all have history of recurrence pregnancy loss. The study was carried out in the department of ultrasound in College of Medical Radiologic Sciences, using general electric Logic 5 ultrasound machine. The data were collected by measuring the PI, RI and PSV values as well as the status of intrauterine condition using a multi-frequency vaginal probe 6-10MHz. The results of this study showed that there is a significant difference in uterine blood flow indices (PI, RI and PSV) for the PRL groups at p = 0.05 using ANOVA test with p <0.001 and F equal to 118.9, 152.7 and 3.6 respectively. The result as well showed that; the mean values of PI, RI and PSV was 2.1±0.9, 0.7±0.4 and 47.7±28.7 for threaten abortion and for elective abortion it was 1.0±0.5, 0.5±0.3 and 56.1±24.9, the non pregnant group was 0.8±0.3, 2.7±1.6 and 54.4±23.9 respectively. The classification accuracy result using Fisher linear discriminant analysis approach to discriminates between the three groups in respect to their PI RI and PSV only as input it was 77.7%. The control group showed that the mean value for PI, RI and PSV was equal to 1.4±0.87, 1.0±0.60, and 60.8±25.63 respectively. These values showed that there is a difference between the control group and the study groups. This difference was significant by using t-test for the entire group versus the control at p = 0.05 except for PSV in the elective group. The t- values for PI of the threaten abortion, elective abortion and non pregnant groups was 8.68, 6.60 and 14.19 respectively. As well the t-values for RI was 2.16, 9.39 and 11.81 respectively, similarly in respect to PSV the t-values was 4.72, 1.73 and 2.90 where the difference was inconclusive in case of elective abortion at p = 0.05 with p = 0.09. Generally the result showed that the RPL groups were different as well as they were different from the control group.