Evaluation of Serum Chromium Level among Type 2 Diabetes Mellitus Patients in Khartoum State

Abstract

This is a descriptive analytical study conducted in Khartoum State during the period from the January to September 2015. The aim of this study is to evaluate serum chromium level of type 2 DM patients and its correlation with study variables (BMI, HbA1c, duration of disease, age, and gender). One hundred and twenty subjects were enrolled in this study; they were classified into 60 type 2 DM patients as case and 60 healthy apparently as control group. Serum chromium and HbA1c level were measured using atomic absorption spectrometry and ICROMATM . The results showed significant decrease in chromium level in type 2 DM patients in comparison with healthy group (p-value 0.000). In addition There was significant increase in chromium level between of good control versus poor control DM patients with ( P-value 0.001).Also the study revealed negative correlation between chromium level and duration of DM ( R-value -0.354) and ( P-value 0.005). Study concludes that, chromium level is significant decrease in type 2 DM, especially uncontrolled DM patients, therefore may exaggerate the complication of DM especially CVD due to, deficiency of chromium causes insulin resistance and decrease in HDL level.