Abstract:
This study was done in Khartoum state in the period of
August to October 2013, to detecting the schistosomiasis
effect on erythropoeisis effectiveness and iron status among
basic school boys (9-17 year old). This study included 82
schistosomic boys and 82 non-schistosomic boys. The
density
of
infection
was
measured
by
formal
ether
concentration technique and urine sedimentation technique.
Five
vinous
blood
had
been
drown
from
all
study
participants, 2.5 ml placed in EDTA container, 2.5 ml placed
in Lithium Heparin container,. EDTA blood sample was used
for CBC which has been carried out using automatic cell
counter (Sysmex Kx 21N), reteculocyte count, and PBP, while
the plasma of
heparinized
blood was collected for iron
profile.
The results of case group were as followed: RBC: 4.6 x 106
cell/μL, Hb: 12.5 gm/dL,
PCV: 36.5%, MCV: 78.5fL , MCH:
26.9 pg, MCHC: 31.3 gm/dL, RDWSD:41.3%, WBC: 7.8 x 10 3
cell/μL, DNC: 31.8%, DLC:38.79%, DMC: 5.7%, DEC: 24.5%,
ANC: 2.4 x 103 cell/μL, ALC: 2.9 x 103 cell/μL, AMC: 0.4 x 103
cell/μL, AEC: 2.1 x 103 cell/μL, platelet count: 432.0 x 103/μL,
PDW: 12.3%, MPV: 10.0 fL, PLCR: 25.1, reteculocyte count:
0.47%, CRC: 0.38%, ARC: 0.017 x 106 cell/μL, RPI: 0.35,
serum iron: 90.3 μg/dL, serum ferritin: 56.8 μg/L, transferrin
saturation percentage: 304.8%, and TIBC: 97.82 μg/dL.
This study concluded that, there was a significant reduction in most of study
variables when compared with control group, there was a significant revers
association between density of infection and all study variables except Plts,
TWBCs, and AEC. S.hematobium infection was
more severe than
S.mansoni form of disease.
This study presented that there is a significant reduction in red cell indices
(MCV, MCH, and MCHC), reduction in erythropoeisis efeectiveness (RPI),
and reduced iron stores (SF) that indicates iron deficiency anemia.
