Abstract:
This is a descreptive, cross –sectional ,analytical study has been carried out in
Algadrif hospital (Algadarif state) from December 2008 to January 2009. The study
aimed to detect the ethnic and geographical distribution of sickle cell anemia in
patients referring to Algadarif hospital . Hundred blood samples were collected into
EDTA blood containers (2-5 ml) from different SCD patients.All samples were
investigated by mythic 18 for CBC and also investigated for Hb type by using of Hb
electrophoresis. Data were analyzed using statistical package program for social
sciences (SPSS).
The study showed that the frequency of SCD was found in Hosa tribe with frequency
of 57% Followed by Falata, Burno, Four, Masalet , Tama and Messeria with
frequency of 18%,9%7%,5%,3% 1%respectively .
Geographic distribution showed that the highest frequency of sickle cell disease was
faund in tribes originated from outside Sudan (Hosa , Falata ,Tama, Burno) with
percentage of 87 % &the lowest was in tribes originated from Kurdufan state
(Messeria) with frequency of (1%) .
Also the study showed that no case was recorded from tribes of North , South and
East of Sudan. The result showed that the percentage distribution of patients
according to Hb type was 53% for AS and 47% for SS.
The results showed that the means of Hb ,RBC,WBC,PLT,HCT,MCV,MCH MCHC
in patients of SCD(Sickle Cell Disease) (SS) were :
7.8g/dl,2.9×
,16.7×
,469×
,21.7%,81.4M
,24.7/Pg,
30.8,respectively and in SCT (Sickle Cell Trait)(AS) were:
,27.2/pg,31.9.respectively.
Also the study showed that normocytic normochomic RBCS were predominant in
peripheral blood of SCD (Sickle Cell Disease)with frequency of 66% followed by
microcytic hypochromic RBCS with frequency 33% and macrocytic RBCS with
frequency of 1%.
