Abstract:
This study was carried out in the order to evaluate the levels
of lipids and lipoproteins in the serum of 100 patients
suffering thyroid disorder. Three groups were involved in this
study. 50 patients suffering hypothyroidism and 50 patients
suffering
hyperthyroidism
and
50
subjects
apparently
healthy and control group have no any history of thyroid
disorder. All the participants were meat at Ed-Dueim city, in
which all the clinical assessment were done by professional
physicians. The biomedical analysis of the samples was
performed at the The Khartoum Teaching Hospital, by used
spectrophotometer (Bio System BTS-310).
When screening the lipids levels in hypothyroidism patients
compared with hyperthyroidism patients, In hypothyroidism
the levels of total cholesterol and LDL-cholesterol were
significantly elevated (P.value 0.000 and P.value 0.000
respectively) than control and exceeded the reference
normal
values,
but
Triglyceride
and
HDL-cholesterol
remained unchanged and within the normal values (P.value
0.48 and P.value 0.72 respectively).
Under
hyperthyroidism
condition
all
lipid
parameters
remained with remarkable alteration and within the normal
reference values.
It
believed
that
the
cause
of
LDL-cholesterol
in
hypothyroidism patients, and this may be attributed to the
increase oxidation, insulin- like growth factor was also
complicated in the increase of LDL-cholesterol.
From this study it is recommended that patients having
hypothyroidism should be treated for hyperlipidemia.
