Abstract:
Tobacco used for manufacturing of toombak is species of Nicotiana rustica
leaves. Tobacco ( Nicotiana rustica) contains carcinogenic N –nitrosamines.
these are formed by N-nitrosation of the major tobacco alkaloids( nicotine
and nor nicotine) during curing and fermentation of tobacco .
Among the N–nitrosamines formed during curing ( processing) of
tobacco : 4-(methylnitrosoamino)-1(3-pyridyl)-1-butanone (NNK) and Nnitrosonornicotine
(NNN) .
This study was conducted to Identify of carcinogenic N –nitrosamines
(NNN and NNK) samples of Sudanese toombak were collected from five
vendors in Bahri . Separated funnel was used to extract N-nitrosamines
from the samples. GC-MS Spectrometry and Thin-Layer
Chromatography (TLC) were used to detect and the identify Nnitrosamines
extract. It was noted that, all the above carcinogenic
compounds were detected in toombak
