Abstract:
Background:
Hypertension is a long-term medical condition in which the blood pressure in the arteries
is persistently elevated. Long-term high blood pressure, however, is a major risk factor
for coronary artery disease, stroke, heart failure, atrial fibrillation, peripheral vascular
disease, vision loss, chronic kidney disease, and dementia
Objectives
This study aims to estimate AST,ALT and albumin in patient with hypertension.
Materials and methods:
This study includes 100 participant, 50 of them have hypertension and the other are
control group,5 ml of blood was taken from each participate to prepare serum, the serum
prepared was used for the measurement of ALT,AST and albumin using BA400
(BIOCHEMISTRY ANALYZER) and the data obtained were analyzed using SPSS
version 20.
Results:
This study included 50 female and male with hypertension and 50 without hypertension
age matched, the mean concentration of AST,ALT, albumin were significantly increased
among hypertensive patient(35.154±2.3184), (35.858±2.6679), (4.000±.3105) in
comparison with control group (23.354±4.5197), (25.478±4.7412), (3.702±.1985)
respectively with p value 0.000 , the mean concentration of AST,ALT was significantly
increased among male group P value(0.002 )( 0.037) respectively in comparison with
female group p value(0.002), ( 0.037)respectively. in contracts there is significant
increase in mean concentration of albumin in female group in comparison with male
group with (P value=0.034).
Person’s correlation showed no correlation observed when associated serum AST, ALT,
albumin with age of hypertension patient (r 0.013,p value 0.927)(r 0.078 p value
0.550)(r 0.107,p value 0.459) and there is no correlation observed when associate serum
AST, ALT with duration of hypertension(r 0.204 p value 0.156)(r 0.239, p value 0.095) ,
and also serum Albumin not correlated with duration of hypertension patient(r 0.112 p
value 0.440).
