Abstract:
This is a cross-sectional descriptive and analytical study, conducted at
Khartoum teaching hospital during the period from March 2010/
September 2010. The aim of this study was to estimate the fibrinogen
level in Sudanese smokers who attended in Khartoum teaching hospital.
Sixty Sudanese healthy smokers were informed about the study and their
agreement for participation was obtained. The study population was
divided in to three groups according to the duration of smoking and
number of cigarettes smoked per day as follows:
The first group was smoking for less than 10 years, the mean of
fibrinogen level was 3.33g/L , while the second group were smoking
for 10 to 20 years, the mean of fibrinogen level was 5.39g/l. And the
third group was smoking for more than 20 years, the mean of fibrinogen
level was 7.14g/l.
According to the number of cigarettes smoked per day the population was
also divided into three groups, the mean of fibrinogen level was 3.41g/l
in the first group who smoked less than 10 cigarette /day, 5.7g/l in the
second group who smoked from 10 to 20 cigarette /day, and 6.97g/l in
the third group who smoked more than 20 cigarette /day.
The results obtained indicated that the fibrinogen level was in the normal
range in the first group according to intensity and duration of smoking.
But in comparison with control group, fibrinogen level was statistically
higher. While the fibrinogen level was much raised in the other groups
and the rise is statistically significant in comparison with control group, p
value=0.000.
Finally, In conclusion the results obtained in the current investigation
proved that smoking increased the level of fibrinogen and the increase in
level is directly related to the duration of smoking and number of
cigarettes smoked/day.
