Abstract:
Corpus callosum is vital part of the human brain because it enhances and
maintains communication between brain hemispheres. It is likely to be
affected by the physiologic, as well as pathological changes occurred in the
regions of brain. Also corpus callosum dimensions and texture might be
change in respect to age which generally might insinuate or simulate
pathology. Therefore Study of normal measurements of corpus callosum is
helpful in providing baseline data for recognizing and diagnosing the
presence and progression of diseases as well as to differentiate between
degenerative changes and pathological changes.
The aim of this work was to provide a Sudanese index (dimension) for
corpus callosum and the associated parts in the normal people and the
changes in the measurement that attributed to ageing and compare it with the
published data.
A number of MRI scans of 50 adult patients (male and female) aged between
10 – 74 years, having no brain disorders that affect the corpus callosum,
were collected from department of radiology at Modern Medical Center Alzaytouna
Hospital, and Royal Care International Hospital.
The results showed that the average genu, trunk and selenium widths are
11.63 +/- 1.77, 6.04+/- 1.18 and 11.37 +/- 1.85 mm respectively.
The study concluded that according to the normal cells adaptation the age
have direct effect on the corpus callosum size and noted that increase in age
lead to decrease in corpus callosum dimensions