Measurment of Hb,HCT,RBCs count and blood indices in Sudanese childeren under 16 years suffering from Chronic renal failure and under dialysis

Abstract

This study was conducted at Khartoum state, at Soba Hospital,Selma Center for dialysis and Khartoum North Center for dialysis.Aquestionnaire was used for direct interview and the objective of the study was cleary explained to all individuals participating in the study. The study included 100 individuals , 80 patients and 20 as control.Blood samples was collected from patients under 16 years suffering from end stage renal failure and under dialysis.2.5 ml of venous blood was collected in EDTA container .The following investigations were carried out (Hb, HCT ,RBCs count ,MCV ,MCH ,MCHC, morphology of the RBCs in stained blood film and detection of the type of anemia) using an automated haematological analyzer(Sysmex). The results showed that there was highly significant decreased in mean of Hb level (9.6 g/dl), mean of HCT ( 29.27% ),mean of RBC× 106/ml (3.5) ,Mean of MCV( 83.05fl), mean of MCH (27.3pg) ,mean of MCHC(32.7g/dl), and the main type of anaemia present was normocytic normochromic anaemia which is caused by deficiency of erythropoietin hormone production by the diseased kidney.There was microcytic hypochromic RBCs in some cases,which might be due to iron deficiency.Also the results showed that there was no significant differences between the mean of Hb and type of dialysis also the duration of dialysis had no effect on the mean level of Hb(P=0.432) ,HCT(P=0.608) and RBCs count?(P=0.206).