Measurements of Plasma Total Protein, Albumin and Urea in Healthy Sudanese Pregnant Women

Abstract

An analytical c study conducted during the period of January to July 2011, to compared serum levels of total protein, albumin, and urea of 80 pregnant women, 18 pregnant women (at first trimester), 23 pregnant women (at second trimester), and 39 pregnant women (at third trimester), 20 health non pregnant women (as control group). Participants in this study were seen at Saudi Maternal Hospital Omdurman, Sudan. Serum levels of total protein, albumin, and urea were measured using Bio System Spectrophotometer 310 and commercial kits from Bio System Company. The result of the study shows that the mean of the serum levels of total protein in first trimester had no significant difference when compared to control group (P=0.055), while serum albumin and urea in first trimester were significantly decreased when compared to control group (P= P=0.007, 0.008). The mean of the serum levels of total protein , albumin and urea in the second trimester was significantly III decreased when compared to control group (P= 0.001, P= 0.000, P=0.000) The mean of the serum levels of total protein , albumin and urea in the third trimester was significantly decreased when compared to control group (P= 0.000, P= 0.000, P=0.000) The result of the study shows that the mean of the serum levels of total protein, albumin in first trimester haves no significant difference when compared to that of second trimester (P= 0.088, P=0.068), while the serum levels of urea was significantly decreased (P=0.046). The mean of the serum levels of total protein, albumin, and urea in first trimester significantly decreased when compared to that of third trimester (P= 0.000, P=0.000, P=0.001). The mean of the serum levels of total protein, urea in second trimester was no significant difference when compared to that of third trimester (P= 0.193, P=0.194), while the serum levels of albumin was significantly decreased (P=0.000).