Frequency of ABO and Rhesus blood group antigens & phenotypes among Al Danagla Sudanese tribe

Abstract

This is a prospective and analytical study, aimed to determine the frequency of ABO, Rh antigen, and phenotypes, among Danagla Sudanese tribe. Also the study aimed at establishe ABO, Rh blood group baseline data for this Sudanese tribe to determine the interaction between this tribe and other Sudanese tribes which will be useful in the blood transfusion. The study was conducted during three months (April to July, 2007), Following informed consent, a total of hundred venous blood samples were collected from unrelated individual into 2.5 ml EDTA containers. All samples were tested for ABO and for common Rhesus antigens using the slide agglutination techniques, and twenty samples were tested by immune-diffusion gel technique. The antigens and phenotypes were determined. Similarities between this tribe and other Sudanese tribes and with other countries were calculated using Jaccard's coefficient of similarities. The results obtained showed that, The O group was most common frequently occurred ( 50% ) , followed by group A ( 32%), group B was found ( 14% ) and least common was group AB ( 4%). The e, c, and the D antigens were the commonest alleles detected with frequencies of 99%, 91% and 91% respectively. The C and the E antigens were the least frequent with 52% and 2% frequencies respectively. There was a marked similarities between the Sudanese tribes that lived in same geographical area this could be due to intermarriage , while the difference that seen in some tribes could be most probably due to the wandering nature of these tribes.