Bacterial Urinary Tract Infections in Diabetic Patients

Abstract

The main objective of this study was to isolate the possible bacterial pathogens from the urinary tract of diabetic and non-diabetic patients (as control). A total of hundred specimens (n=100) were collected from Jabir Abuliz Specialized Center for diabetic patients, Khartoum North Teaching Hospital and Police Hospital. Samples were collected from both males and females at different ages and then cultured and incubated at 370C for overnight. Isolated bacteria were identified by Gram stain and biochemical tests. The most common isolated bacteria among the diabetic Patients were Escherichia coli (16%), followed by Klebsiella pneumoniae (10%), Staphylococcus aureus (8%) Pseudomonas aeruginosa (6%), Staphylococcus saprophyticus (4%), Proteus mirabilis (2%) and Enterococcus faecalis (2%), E. coli were the most prevalent bacteria (42%) isolated among non- diabetic patients, followed by S. aureus (12%), K. pneumoniae (8%), P. aeruginosa (6%) and P. mirabilis (4%). The study showed that among diabetic patients, infections of females were fairly high (70.8%) compared to male patients (29.1%). However, prevalence of infection was significantly higher (P < 0.05) among non- diabetic females (75%) than diabetic females. Most isolated Gram – negative bacteria were sensitive to trimethoprim, ciprofloxacin, nitrofourantoin, nalidixic acid, ceftazidime and ampicillin except P. aeruginosa, P. mirabilis, which were resistant to ampicillin among diabetic patients. Furthermore, the most isolated Gram –positive bacteria were sensitive to gentamicin, vancomycin and penicillin except S. saprophyticus and E. faecalis among diabetic patients and S. aureus among non-diabetic patients.