Screening for breast cancer among women with breast lumps using cytological methods and demonstration of DNA

Abstract

This study was conducted in radiation and isotopes center Khartoum (RICK), from February to April 2005. The study was aimed to screen for breast cancer among women presenting with palpable lumps, to determine the incidence of breast cancer among women attended to (RICK) with breast lumps using fine needle aspiration (FNA) and to detect the ratio of Deoxyribonucleic acid (DNA) among patients. One hundred specimens were collected from fifty patients from different age. Fifty specimens were stained with May-Grun Wald Giemsa Technique concluded that (8%) were carcinoma, (12%) inflammation and (80%) benign tumors. The mean of the ages among patients with carcinoma and inflammation is (49) years and (35) years in benign tumors. After staining with acridine orange, the DNA ratio seemed to be normal in inflammation and benign cases but was increased in carcinoma.