THE EFFECT OF THYROID DYSFUNCTION ON GLUCOSE LEVEL

Abstract

The concentration of blood glucose and the thyroid gland hormones in 50 patients suffering thyroid disorder and in 10 apparently health persons (control) were monitored. The patients and control were met at Khartoum Teaching Hospital. They are similar in age and including 39 of the suffering hyperthyroidism and 11 of hypothyroidism. All patients and control were seen at Khartoum Teaching Hospital where the clinical examination and chemical analysis were done. The results obtained from this study indicated that patients with thyroid disorders have clear signs and symptoms of the thyroid disease, and all patients were females which indicate that disease is more common among females than males. The study presented data indicating that alteration in thyroid gland hormones existed. TSH level was found to be increased in thyroidism patients over control value, with nearly a constant level in T3 or reduction level in T4. In hypothyroidism patients, over production of TSH was observed with clear underproduction of T4 and unchanged level in T3 . In hyperthyroidism, decrease of TSH value with an increase of T4 and unchanged level of T3 were also evident. The study also showed that blood glucose concentration in thyroidism patients (hyperthyroidism and hypothyroidism) was altered and was observed to be an increase in hyperthyroidism than normal range. State of hyperglycaemia and hypoglycaemia was presented but not significant. The study also indicated that blood glucose was negatively correlated with TSH in hypothyroidism and hyperthyroidism and positively correlated with T4 and T3.