PLASMA PROTEINS IN HEALTHY SUDANESE PREGNANT WOMEN Astudy in Sudan- Gezira State

Abstract

In this study, a total of 80 persons were examined for total serum protein, albumin, globulin levels and protein electrophoresis, a control group of non- pregnant women (n=30), and a pregnant women group (n=50) which was divided into three subgroups according to the duration of pregnancy (first trimester subgroup “n=15”, second trimester subgroup “n=15” and third trimester subgroup “n=20”). The results obtained showed that: -There was no significant difference between the means of total serum protein in pregnant women group and the control group: (6.7 ± 0.41 versus 7.1 ± 0.47, P > 0.05). -There was no significant difference between the means of serum globulin in the pregnant women group and the control group: (2.8 ± 0.38 versus 2.7 ± 0.35, P > 0.05). -There were no significant difference between the means of total serum protein, albumin and globulin in the first trimester subgroup and the second trimester subgroup: (6.6 ± 0.36 versus 6.7 ± 0.41, P > 0.05), (4.0 ± 0.38 versus 3.9 ± 0.35, P > 0.05), and (2.6 ± 0.72 versus 2.7 ± 0.36, P > 0.05) respectively. -There was no significant difference between the means of total serum protein in the first trimester subgroup and the third trimester subgroup: ( 6.6 ± 0.36 versus 6.6 ± 0.42, P > 0.05). -Also there was no significant difference between the means of total serum protein in the second trimester subgroup and the third trimester subgroup: ( 6.7 ± 0.41 versus 6.6 ± 0.42, P > 0.05). Also this study showed: -There was significant difference between the means of serum albumin in the pregnant women group and the control group: (3.8 ± 0.36 versus 4.4 ± 0.29, P < 0.05). -There was significant difference between the means of serum albumin in the first trimester subgroup and the third trimester subgroup: (4.0 ± 0.32 versus 3.6 ± 0.18, P < 0.05). -There was significant difference between the means of serum albumin in the second trimester subgroup and the third trimester subgroup: (3.9 ± 0.36 versus 3.6 ± 0.18, P < 0.05). -There was significant difference between the means of serum globulin in the first trimester subgroup and the third trimester subgroup: (2.6± 0.27 versus 3.0 ± 0.4, P < 0.05). -Also there was significant difference between the means of serum globulin in the second trimester subgroup and the third trimester subgroup: (2.7± 0.36 versus 3.0 ± 0.4, P < 0.05). -There were no characteristic changes in the five bands of the electrophoretic patterns of the pregnant women group and the control group. These results mean that: Serum proteins levels are affected by pregnancy and its duration, but electrophoretograms are not.