Measurement of PT, APTT and Platelet count of patients with type 1 Diabetes Mellitus attending Abu Aagla Center in Wad Medani

Abstract

This is a cross sectional study, conducted in Abu Aagla center in Wad Medani from 9 /April /2012 to 2 /May /2012, to measure PT, APTT and platelets count of type 1 diabetic patients study population, 4.5ml venous blood collected from fifty of type 1 diabetic patients in trisodium citrate anticoagulant to measure PT and APTT and 2.5ml in EDTA to measure platelet count The research reveal the flowing results: There was insignificance different in PT in the patients group compared to control group (P value=0.73), insignificant increase according to the duration of disease (P value=0.15), there was insignificant difference in PT/second according to insulin dose received per day, (P value =0.18), there was insignificant difference in PT/second of diabetic patients with hypertension compared with to control (P value=0.09) and there was insignificant increased in PT/second according to onset of disease compared to control group (P value =0.18). There was a significant increase in APTT/second of patients mean (57.9±SD) compared to control group mean {29.5±SD)/second, (P value=0.00). Insignificant difference was associated with duration of the disease (P value=0.54). Insignificant difference in APTT/second according to insulin dose received per day (P value=0.96). Insignificant difference of APTT/second in diabetic patients with hypertension compared to control group (P value=0.72). There was significant increase in APTT/second according to onset of the disease mean (57.9±SD)/second, compared to control group mean (29.0±SD) /second, (P value=0.00). There was significant increase in platelets count×10 9 /dL in the patients mean (216±SD) ×109/L compared to control group mean (166±SD) ×10 9/L, (P value=0.00). Insignificant difference in duration of disease (P value =0.41). Insignificant decrease of parameters according to insulin dose received per day (P value=0.28). Significant decrease in diabetic patients with hypertension mean (197.3±SD) ×109/L, compared to control group means (227.4±SD) ×109/L (P value= 0.03). Increase significantly according to onset of the disease mean (216.5±SD) ×109/L, compared to control group means (166.4±SD) ×109/L, (P value=0.00).