Estimation of Some Hemostatic Parameters Among Sudanese Patients With Diabetes Mellitus Type 2 in Alrakha Hospital - Khartoum

Abstract

This study was a cross sectional study ;conducted in AL Rakha hospital , from 5/5/2012 to5/6/2012 to estimate PT, APTT, TT, Fibrinogen level , D-dimer a mang patients of diabetes mellitus typeII . 4.5ml venous blood collected from fifty patients of diabetes mellitus typeII in trisodume citrate anticoagulant , the result compared with thirty normal healthy non diabetic individuals and collected data were analyzed by Statistical package of social science (SPSS) , the research revealed the following results: There was insignificant difference of PT/second in diabetic patient typeII when compared with control group (P value > 0.05),also there was insignificance prolongation of APTT in diabetic typeII when compare with control group (p value > 0.05). Significant increased in TT/second , fibrinogen level and D-dimer in the diabetes patients when compared with control group (P.value.00) . Also there were insignificance difference of PT/second, APTT/second,TT Fibrinogen level and D–dimer in male ,when compared with female the study reveal the (P value> 0.05). Also there were insignificance difference of PT/second, APTT/second,TT ,Fibrinogen and D–dimer in duration of disease with (P value>0.05) ). Also there were insignificance difference of PT/second, APTT/second,TT Fibrinogen and D–dimer age group (P value >0.05), The results obtained indicated that measurement of thrombin time (TT),fibrinogen, and D-dimer were necessary when evaluating patient with diabetes mellitus typeII there was clinical evidence of hemostatic abnormality.