Measurement of Haemostatic Parameters and Haemoglobin level in visceral leishmaniasis Patients Attending Al-Gdarif Teaching Hospital

Abstract

This is an analytical case-control study, conducted at Al- Gdarif Teaching Hospital during the period from January to April 2010. The aim of this study was assessment of the haemostatic parameters (platelet, PT, APTT and TT) and haemoglobin, tests in visceral leishmaniasis patients attended Al-GadarifTeachingHospital. Fifty visceral leishmaniasis patients were informed about the study and agreed for participation. The study population was divided into two groups according to sex, 5 groups according to age, 15 groups according to tribe. Five ml of venous blood was bleed 2.5mlin EDTA containers and 2.5 ml in tri sodium citrate containers and investigated for the Hb level, platelet count, PT, APTT and TT tests. Fully automated haematological analyzer Sysmexwas used for Hb, platelet, and manual analysis for PT, APTT and TT. All visceral leishmaniasis patients had mean values of Platelet=115.000cell/mm3 decrease significant than control mean value = 198.000cell/mm3,PT=16.4second, prolong significant than control mean value = 14.5 second, P.value = 0.029. INR=1.5, increased but not significant than control mean value = 1.4, P.value = 0.288.APTT=31.8second, prolonged significant than control mean value = 28.3,P.value = 0.001.TT=9.3second, prolonged than control mean value = 9 second but in significant, p. value = 0.46.andHb = 8.4g/dl,decrease significant than control mean value of Hb 13g/dl, P.value = 0.000.