Assessment of complete blood counts in patients of chronic renal failure in Khartoum teaching hospital

Abstract

This study was hospital analytical case control , and it was conducted to determine haematological cells parameter among the adults Sudanese patients with chronic renal failure and whom on long term haemodialysis . 60 patients were informed about the study ,expected out come and agreement of participation were obtained , then the questionnaire was used to collect the information about patients age ,sex ,economical status ,frequency of dialysis ,status of associated iron and or erythropoietin therapy , and history of blood transfusion . As well 4 ml of blood were taken from the patients pre dialysis in non vacuttanerK3 EDTA anticoagulant and it were used to evaluate cells blood counts , fully automated Sysmex kx21 were used to achieved the complete blood counts. Computerized statistical package for social sciences version 11.5 were used to determine the samples size, and in subsequent data processing. The mean age of patients having chronic renal failure were 39 years. the results showed that 83.3 % were anemic and only 16.7 5 were normal ,the mean of haemoglobin level, total erythrocyte counts , Packed cell volume ,Mean cell volume , Mean cell haemoglobin , Mean cells haemoglobin concentration ,total White blood cells counts , Platelets counts , and Main platelets volume were , 9.3783 , 3.1617 , 28.2467 , 87.5967 , 29.3467 , 33.1400 , 6.2250 , 179.883 , and 9.6683 Respectively. For means of haemoglobin value , Red blood cells counts , and packed cells volume there were a higher level of significant variation in compared with control i.e. the significant were 0.000 , 0.000 , 0.000 , for MCV there wasn’t significant variation between the patients and control i.e. the significant were 0.457 . for White blood cells there wasn’t significant variation because the significant level were0.308 , and lastly for Platelets count and Mean Platelets volume there was a higher significant level 0.000 , 0.000 3.637 Respectively . In conclusion the cells blood counts and its parameters are extremely Decreased as results of chronic renal failure.