ANTIMICROBIAL SENSITIVITY PATTERNS OF BACTERIAL ISOLATES FROM ORTHOPEDIC AND UROLOGY UNITS IN KHARTOUM TEACHING HOSPITAL

Abstract

This study was conducted in Khartoum teaching hospital during the period from May to July 2005. A total of 109 patients (with mean age 36 year, range 5-85 years) were included (50 from urology & 59 from orthopedic units). Specimens (urine and wound swab) were collected from each subject (urine & swab) and processed for isolation of the bacterial cause. The isolated bacteria were identified then subjected to antimicrobial sensitivity test using Kirby-Bauer technique. A total of 87 bacterial isolates were identified in the two units. In urology unit, the most common pathogens were E. coli 18 (51.4%) and Pseudomonas spp 8 (22.9%). In orthopedic unit the most common pathogens were Staphylococcus aeureus 19 (36.5%), E. coli 10 (19.2%), Pseudomonas spp 9 (17.3%) ,Proteus spp 9 (17.3%) and Coliforms were 5 (9.7%) . The antimicrobial susceptibility of the 87 isolates to the commonly used 19 antimicrobial agents were performed using the standard Kirby-Baur method. The isolated organisms in urology unit showed high resistance to Ciprofloxacin, Cefuroxime and Cotrimoxazole. And high susceptiblity to Imepenim & Meropenem. The isolated organisms in orthopedic unit showed high resistance to Gentamicin and high sensitivity to Imipenem & Meropenem.