Measurement of Prothrombin Time and Activated Partial Thromboplastin Time among Sudanese Schistsomiasis Patients in Khartoum State 2013

Abstract

This is descriptive cross sectional study which was carried out in Khartoum state, in period from March 2013 to August 2013 to assess the effects of schistosomiasis in coagulation cascade parameters. 50 diagnosed schistosomiasis patients and 25 healthy individuals whole were selected as study group after agreement of participation in this study. 4.5ml of venous blood was drawn from each participant in this study, placed in 0.5 tri sodium citrate container, then centrifuge to get platelets poor plasma (PPP) to assess Prothrombin time and Activated Partial Thromboplastin Time. The results were analyzed using SPSS version14.0, and the mean of each parameter was calculated. The correlation of PT level between case and control group show signcant increase in mean of PT among case group (18.9 sec) and control group (14.1 sec) with P.value (0.000). The correlation of APTT level between case and control group show signcant increase in mean of APTT among case group (51.2 sec) and control group (36.2 sec) with P.value (0.000). The study indicated there was an effect of schistosomiasis on coagulation cascade.