Jaundice Evaluation in Adult Sudanese Patients with Cancer

Abstract

This is a prospective study conducted during the period May 2005 to January2006 to determine type of jaundice in adult sudanaces patients with cancer by estimating the liver function and serological of hepatitis B&C Virus. The population studied include patient with different types of cancer, and having jaundice who had attended the Radiation and isotope center Khartoum (RICK) also from Ibn sina hospital. Samples from 50 patients from different types of cancer including oesophagus comprised 1%, stomach cancer comprised 1%, breast comprised 1%, rectum comprised 1%, cervix comprised 1%, non Hodgkin, s lymphoma comprised 2%, lymphoma comprised 1%, gallbladder comprised 6%, leukemia comprised 9%, pancreas comprised 10%, the primary hepatocellular carcinoma comprised 6%, and metastatsis to liver comprised 14%, and, from 50 apparently healthy individuals as control had taken, then the total plasma protein concentration mean 14.2g/dl, albumin concentration mean 7.0g/dl, globulin concentration mean 701g/dl, total bilirubin concentration mean 9.7mg/dl , direct bilirubin concentration mean 5.7mg/dl, indirect bilirubin concentration mean 4.1mg/dl, enzyme ALP concentration mean 325.6u/l, GPT concentration mean100.1u/l , GOT concentration mean 70.2u/l, γ-GT concentration mean 60.3u/l,and surgical hepatitis B&C virus were estimated in order determine the cause of jaundice is it due to the primary tumor, metastatasis or blood transfusion or due to complication of treatment either chemotherapy or radiotherapy.