Frequencies of ABO and Rhesus Blood Group Antigens and Phenotypes among ALmanaseer Sudanese Ethnic Group

Abstract

This is descriptive and cross-sectional study which took place in northern state of Sudan in amree algadida villages (Villages 2, 3, 4). The study aimed to determine the frequencies of ABO & Rhesus blood group antigens and phenotypes among Almanaseer tribe. ABO& Rhesus blood group baseline data for this tribe could be established and compare with other Sudanese tribes. This study was conducted during the period of three months; between April and July, 2007. Following informed consent, a total of one hundred venous blood samples were collected from unrelated individuals into 2.5 mls EDTA containers. The red blood cells were tested for ABO by the slide agglutination techniques & common Rhesus antigens by the Particle gel immune diffusion and 30% of specimens were tested by the slide agglutination techniques. The alleles and frequencies were determined. Results were analyzed by SPSS program and the similarities were determined by using jaccard Rule. The antigen O was the most common antigen among the study group (50%), followed by B (28%), A (18%), and the least common antigen was AB (4%). The e, c and the D genes were the commonest alleles detected with frequencies of 98%, 91% and 91% respectively. The C antigen and the E antigen were the least frequent with 52% and 27% frequencies respectively. Similarities between Almanaseer and some Sudanese populations and differences with others were noticed.