The Value of Plasma Uric acid, Urea, Creatinine and Electrolytes in Diagnosis of Pre-eclampsia

Abstract

A prospective study conducted during the period of March 2005 to October 2005 to evaluate some of the renal functions in preeclamptic toxemia of pregnancy by measuring blood urea, creatinine, uric acid and electrolytes (Na+, K+). The population of the study includes 25 apparently healthy pregnant women and 50 pregnant ladies proved to have preeclamptic toxemia. Blood samples were taken and plasma was separated. Urea, creatinine, uric acid, sodium and potassium were determined. The result obtained for both groups were statistically analyzed using ‘t’ test correlation. The result obtained from this study showed that there were significant difference between uric acid levels in normal pregnancy and preeclamptic pregnant women (mean difference 3.4 mg/dl and P <0.05) while in urea, creatinine, sodium and potassium there were no significant differences (P>0.05). Uric acid measurement showed that there was a correlation between preeclampsia and uric acid level in blood. Complete renal damage was found to be very rare.