Lipid profile in Sudanese with long standing diabetes type II

Abstract

A descriptive Study conducted during the period, march to June 2007, compared serum levels of total cholesterol, triglyceride , HDL- cholesterol and LDL- cholesterol , of 50 known as patients of long standing diabetes mellitus type II as a test who were selected randomly from Jabir Abuliz specialized diabetic center in Khartoum,and and 30 healthy non-diabetic as control group, controls were selected randomly to be matched with age and sex with that of the diabetic group. The serum levels of total cholesterol, triglyceride, and LDL- cholesterol, all were highly significantly raised (p < 0.05) in the test group (diabetics). When compared to the control group. Mean ± SD for control versus diabetic group were found to be : ( 110.53 ± 31.94 versus 221.34 ± 36.41 mg/dl) ; for serum total cholesterol. (103.57 ± 26.16 versus 179.28 ± 69.67 ) mg/dl ; for serum triglyceride. ( 75.00 ± 29.34 versus 183.74 ± 42.96) mg/dl ; for serum LDL-cholesterol. The serum levels of HDL- cholesterol was found to be significantly reduced (p< 0.05) in the test group compared to the control group. (47.30 ± 6.34 versus 38.44 ± 8.44) mg/dl ; for serum HDL-cholesterol . Correlations: In this study, it is concluded that, long standing diabetes type II is associated with hypercholesterolemia, hypertriglyceridemia, increased levels of LDL-cholesterol and low levels of HDL-cholesterol, these results for Sudanese diabetic patients agree with those reported outside Sudan, the serum levels of total cholesterol, LDL and triglyceride increase with the increase of the duration of the disease while the HDL is reduced, hence, with increase risk for atherosclerosis and coronary heart disease.