Platelets Count and Indices among Sudanese Ischemic Heart Disease Patients in Khartoum state

Abstract

This is a case control study carried out in Sudan heart center in Khartoum state during the period from April to August 2013, the study aimed to measure platelet count and platelet indices. In this study 180 individuals were included, 120 used as a patient their age range from 32 to 75 years and 60 individuals as a control group. EDTA anticoagulated venous blood samples were collected from known diagnostic ischemic heart disease patients and control group. The patients were classified into 2 groups' stable and unstable ischemic heart disease patients. The samples were analyzed by using automated hematological analyzer to measure platelet count and platelet indices (Mean Platelet Volume, Platelet Distribution Width and Platelet Large Cell Ratio). This study showed that there was significant difference in mean of platelets count and Platelet indices (MPV and PDW and P-LCR) between unstable ischemic heart disease patients and control group (P.value ≤ 0.05). The study also revealed that there was significant difference between mean platelet count of stable patients and normal control group (P. value ≤ 0.05). While there was no significant difference between mean of platelet indices of stable patients and normal control group with (P.value ≥ 0.05).