Frequencies of ABO and Rhesus Blood Group Antigens and Phenotypes in Alnuba Sudanese Ethnic Group

Abstract

This was descriptive, prospective and analytical study conducted in Khartoum State in the period of March to June 2007 to determine ABO and Rh phenotype frequencies among Alnuba Sudanese population, this study was included hundred (100) unrelated volunteers from (Aluoba) tribe, in different ages and both sexes (Males and Females), the consent of the selected individuals to the study was taken after being informed with all detailed objectives of the study and its health emphasis in the future. The questionnaire was specifically designed to obtain in formations about name, sex, tribe, age, living place, origin place, telephone and present of pathological condition. The laboratory method used to demonstrate ABO Ags was manual slide method by use convention ABO anti sera ,where manual tube method was used for Rh Ages in addition to automated techniques ( Gel Immune Diffusion ). The percentage of ABO Blood group among Alnuba Tribe were found to be 60 % of them were group O , 29 % group A, 10 % group B, and 1 % group AB . The result showed high frequency of group O and Low frequency in group AB, the percentage of (positive – negative) Rh Fisher classification antigens demonstrated as 92 % of the study groups were positive D antigen, while 8% of them were negative. C antigen positive in 6% and 94 % of them were negative. 97% of Alnuba tribe was positive c antigen while 3 % of them were negative. E antigen positive was found in 9 % and negative was in 91% of them. e antigen positive in 92 %, and 8 % of them were negative ,the most common ABO blood group was group O while AB was the less common ,but the most common Rhesus phenotype was c,D, e in contrast C,E found with low frequencies among the study group. The collected data analyzed using SPSS computerized programmed to calculate the percentage and frequencies of these Ags. The results of ABO and Rh (D) Ags in this study showed similarity With others studies included distribution of blood groups among city Mashhad in North East of Iran and frequencies among Yoxuba and Hausa in Nigeria.