Assessment of plasma Zinc and Magnesium Levels among Sudanese Hemodialysis Patients in Khartoum State

Abstract

Descriptive cross-sectional study was conducted in the Renal Center for Kidney Dialysis, Khartoum state, The aim of the present study is to assessment the plasma zinc and magnesium levels among haemodialysis patients (before and after haemodialysis with controls (age & sex &duration of dialysis). - A total of 40 individual with chronic renal failure were enrolled in this study, in addition to 20 healthy volunteers’ subjects as a control group. Method: atomic absorption spectroscopy device was used for measurement of zinc. spectrophotometeric assay was used calcium estimation, then data were analyzed by Statistical (SPSS version 16) computer software - The results of the present study showed a significant increase in the mean of zinc level in hemodialysis patients beforedialysis(4.5±1.19) when compared with control group (0.95±0.17) and significant decreased after dialysis (4.03±0.99) with (P-value < 0.001). Result of magnesium indicated significant increased when compared mean of hemodialysis patients before and post dialysis (2.08±0.12), (2.09±0.16), (1.8±0.35) when compared with control group respectively with (P-value <0.001).In this study there was no correlation between zinc and age( r = 0.012, p.value =0.34)& duration of dialysis (r = 0.009, p.value= 0.93). Also there was no correlation between magnesium and age (r = 0.057, p.value = 0.033)& duration of dialysis (r = 0.187, p.value = 0.098). In Conclusions plasma zinc and magnesium levels are significantly increased in hemodialysis patients than in controls. No significant difference in plasma magnesium level betweenpre and post hemodialysis and significantly decreased zinc level between after hemodialysis patients