Prothrombin and Activated Partial Thromboplastin Times among Hypertensive Patients in Khartoum state

Abstract

This analytical case control study was done during the period of March 2012 to July 2012 in Khartoum state military hospital to determine the PT, APTT among hypertensive patients seventy patients (70) and thirty (30) normal controls were studied. A structured questionnaire was prepared which included the general information and laboratory investigation and an informal consent was obtained. Blood, plasma samples were collected from hypertensive patients and normal healthy control for use in laboratory investigation. The result shown non significant difference (P= 0.22) between the mean level of hypertensive patient (15.3 Sec) and control (15.5 Sec) in prothrombin time (PT), and there is non significant difference (p= 0.20) between the mean level of hypertensive patient (32.4 Sec) and control (33.4 Sec) in activated partial thromboplastin time (APPT). The Result obtain indicated that measurement of prothrombin time (PT) and activated partial thromboplastin. (APTT) were unnecessary when evaluating a hypertensive patients in whom there was no clinical evidence of haemostatic abnormality an approach would eliminate the need for most of coagulation test done in these patients such as D.Dimar and Fibrinogen level.