Effect of Haemodialysis on Glucose Level in Sudanese Patients with End- Stage Renal disease

Abstract

This study was carried out on 63 patients (41 males, 22females) with end stage renal disease (ESRD) aged from 14 to 74 years and were on haemodialysis. All patients were seen at Dr. Salma center for renal dialysis and transplantation (Khartoum). Glucose concentration was measured pre and post haemodialysis in the blood of all patients inorder to study the influence of the renal haemodialysis on the concentration of blood glucose and to asses if there was any change and to predict suitable precautions that might be taken so as avoid the risk of that change accompanied the renal haemodialysis. The preliminary investigations revealed that most of the end stage renal disease patients were presented with other disease, namely hypertension, diabetes mellitus, renal stones, hepatitis (HBV) and tuberculosis (TB). The findings of this study showed that the level of blood glucose concentration of the majority patients changed after the session of haemodialysis, most of this change was reduction in the concentration of glucose. The findings also revealed that age had no impact on the level of blood glucose pre- and post haemodialysis. It is obvious from this study, that the blood glucose should be estimated before the initiation of the session of the haemodialysis so as to avoid the risk of hypoglycemia. The study also revealed that both males and females showed over all reduction in the concentration of their blood glucose post haemodialysis with slight tendency to reduction in female compared with male .(male p=0.004) (female p=0.012). The findings also revealed that the age intervals had no impact on the difference in blood glucose pre- and post haemodilysis. It is obvious from this study that the estimation of blood glucose should be done for all ESRD patients (diabetic and non diabetic) before and after the session of haemodialysis and their blood glucose should be adjusted within the normal range. The findings of this study showed that the level of blood glucose concentration of the majority of patients changed after the session of haemodialysis most of this change was reduction in the concentration of blood glucose. This occurred in spite of that the dialysis solution in the dialysis machine, which was responsible for the withdrawal of waste products was treated so as to avoid any undesirable change in blood glucose. Both diabetic and non diabetic are prone to hypoglycemia post haemodialysis. So checking and monitoring their blood glucose is very vital .for their lives