Assessment of Thyroid Hormones Level in Thyroid Patients Using Radio Immune Assay RIA

Abstract

In this study 14227 Sudanese subjects attended the RadioImmunoAssay laboratory at RasioIsotope Centre Khartoum (RICK) for thyroid function test during the period from 1/1/2005 to 31/12/2005. The test included serum analysis for thyroid related hormones which are thyroxin (T4), triiodithyroinine (T3) and thyroid stimulating hormone (TSH). The patients were referred to (RICK) from different hospitals and clinics in Khartoum state. The main objective of this study was to determine the incidence of thyroid gland abnormalities among the Sudanese subjects sent for thyroid hormones analysis and to find out the most affected age and sex of the patients among them. A further objective was to evaluate the thyroid gland disorders based on its related hormones. The age of the patient varied from less than 1 year up to more than 60 years. Patients were firstly divided into two groups according to their gender and then divided according to their age into 7 groups with 10 years intervals in order to study the demonist thyroid disorders in each gender and age interval (the risk group). All statistical analyses in this study were performed using SPSS software, version 13.0 (SPSS Software, Chicago,, USA). The results obtained in this study indicated that thyroid disorders were more common among female than male with a ratio of about (4:1). It was also observed that the most common affected group were the subjects between 20-30 years old (41.5%) followed by those aged between 30 to 40 years which represented 26.6% of the total patients.