Diagnosis Of Epilepsy Using MRI

Abstract

The purpose of this study was to detect epilepsy using MRI as volumetric tools to measure hippocampal volume and area. In addition to determine whether or not there is a relation between age and seizure onset, duration of epilepsy, seizure frequency, and treatment on patients with epilepsy. 29 patients were diagnosed with temporal lobe epilepsy according to EEG result and clinical data underwent MR imaging. 17 control group were studied retrospectively, absolute and normalized hippocampal measurement were compared between the patients and control group. T1andT2 weighted images in oblique coronal plane were obtained for consecutive patient ( 11 male & 18 female) compared with control group (6 male & 11female). The volume and area of hippocampus were quantitatively measured using manual tracing. The radiologist independently reviewed the MR imaging findings of the hippocampus regarding atrophy, abnormal signal intensity, on each side. High signal intensity (75.9%) of the hippocampus in T2 weighted MR images in patients with epilepsy when low signal was visible in control group. The volume was found to be smaller in epileptic patients compared with the healthy control. There were mild decreasing in seizure frequency according to anti epileptic drugs in patients with epilepsy. The study findings support the view that high signal intensity on T2 and hippocampus reduction are associated with epilepsy.