A Base line of Complete Haemogram, Prothrombin Time and Activated Partial Thromboplastin Time in Sudanese Pregnant Women at Khartoum Teaching Hospital

Abstract

This is a cross-sectional descriptive and analytical study, conducted at Khartoum Teaching Hospital during the period from first of November 2009 to the first of April 2010. The aim of this study was to estimate the complete hemogram, prothrombin time and partial thromboplastin time tests in Sudanese pregnant women who attended Khartoum Teaching Hospital (Obstetric Ward). 50 Sudanese apparently healthy pregnant women were informed about the study and agreed for participation was obtained. The study population was divided into three groups according to the trimesters as follows: Pregnant women at first trimesters were 30%, second trimesters were 32%, and third trimesters were 38%. Venous blood of 5 ml was bleed (2.5ml in EDTA containers and 2.5ml in trisodium citrate containers) and investigated for the count of red blood cells, white blood cells, platelets, hemogloabin, prothrombin time and partial thromboplastin time tests. Fully automated hematology analyzer (sysmex) was used for the CBC analysis, and manual analysis for PT and PTT tests. All pregnant women had mean values of WBCs = 7.580 cell/mm3 RBCs = 4.1 x 1012 Hb = 11.7g/dl Platelets = 256x109 PT = 13.4 seconds and PTT = 36.2 seconds. The results indicated that RBCs, Hb, Platelets and PT showed slight decrease than normal mean value, while PTT results was slightly increase than normal mean value but this decrease and increase in this parameters was statistically insignificant. WBCs mean value was slightly increased than normal mean value and this increase was statistically significant between the three trimesters with the peak in the second trimester.