Comparative Study for Thyroid Abnormalities Assessment using Tc 99m and RIA

Abstract

The study was conducted at the department of Nuclear Medicine at the Radiation and Isotope Center of Khartoum RICK during the period from October 2009 to June 2010 . The aim of the study was to evaluate the abnormal thyroid by using 99m Tc uptake and Radioimmunoassay for 50 patients, they were selected randomly from the daily clinic to the department ( 39 female and 11 male ) . The mean age of the paƟent was 41,8± 15,1 which is range from 12 to74 years. The result showed that, variable disorder like diffuse goiter , multi nodular goiter , diffuse simple goiter, cold nodule and hot nodule. There is higher incidence of thyroid abnormality in female than male 4:1, while 50% of paƟent their age range from 21-40. The shape of thyroid (i.e. regular and irregular) and homogeneity of radiotracer (i.e. homogeneous and inhomogeneous) has no effects on the T3, T4, TSH and uptake. But these quanƟƟes were affected by the age factor in a linear fashion; inversely with the TSH and uptake, and directly with T3 and T4. As well the thyroid uptake was linearly associated with the T3 and T4 inversely, while with TSH was directly.