A Study of Cerebrum and Cerebellum Anatomical Dimensions in Sudanese using Magnetic Resonance Imaging (MRI)

Abstract

This cross sectional descriptive study was done to measure the cerebrum and cerebellum structures. As well it was carried out to establish normal Sudanese reference values for cerebrum and cerebellum dimensions using Magnetic Resonance Imaging (MRI). The study was done at Yastabshron Medical Center (Omdurman) during period 2014-2018 using MRI machine1.5 Tesla. All MRI images were obtained with multi scans, axial, sagittal and coronal with FSE, T2 weighted image and FLAIR techniques. The sample was divided into two groups: group one was 100 healthy participants 39% were males and 61 % were females, their mean age was 42.36±17.87 years old (Min=14.00, Max=80.00 years). In group one; linear measurements were taken for Cerebellum and cerebrum, in Axial and coronal scans; length and width for each hemisphere were taken, as well as maximum width and maximum length were also been measured. In Sagittal scan the Anteroposterior (AP) vermin diameter and width were measured. The study results showed that the cerebrum length was affected by age significantly at p=0.004; however no age related differences were noticed in the cerebellum measurements. The degree of the reduction in the cerebellar measurements is (3-4) mm and unlikely to be significant. Measurements of cerebellum and cerebrum were noticed to be less in females than males, where the cerebellum hemisphere maximum width and cerebrum length were affected significantly by gender, while the cerebellum height and AP vermin width were not significantly correlated with gender. Group Two was another 100 participants where the Cerebellum volume and vermin area were measured, In this group 41% were males and 59% were females. The mean cerebellum volume was 190.6 cm3± 21.57. There is no significant relation between cerebellum volume and age where a significant relation was found with gender and at p=0.000 .The vermin area is greater in males with average 115.4±18.88cm2 than females with average of 111.1 ±19.73 cm2 .The study found that there is no significant relation found between vermin area, age and gender. This study provide a valuable addition to the normative database of the cerebellar and cerebrum anatomy for Sudanese .These data are an attempt to support the norms of the cerebellum data measured in axial and sagittal images. In addition this study showed that Sudanese have a larger cerebellum volume compared with other population.