Evaluation of Lipids Profile among Sudanese Patients with Hypothyroidism in Khartoum State

Abstract

Background: Hypothyroidism has a great impact on lipids as well as a number of other cardiovascular risk factors. Hypothyroidism is relatively common and is associated with an unfavorable effect on lipids.. Objectives: This study is done to assess the levels of lipid parameter in patients with hypothyroidism and to study the relation between hypothyroidism and lipid profile. Material and methods: Astudy was carried out at Khartoum state (asia hospital) , during the period of April to July 2018,including 100 study group , All of them were clinically diagnosed with hypothyroidism . The plasma level of lipid profile were analyzed in fresh samples among volunteers by digital colorimeter instrument and data were analyzed used (SPSS) in computer program. Results: There were significant increase in plasma level of (TC and LDL) and insignificant different in plasma lvel of (HDL) between patiens with hypothyroidism compare with the normal range. Conclusion:From this study shows significant increase in( TC and LDL) (Mean±SD = 235.7±44.9, 154.3±43.1,P≤0.05). and in significant different in (HDL) ( Mean±SD = 23.9±8.1 , P ≥ 0.05 ). between hypothyroidism patients compare to normal range . Also showed the Prevalence of the hypothyroidism is more in elder female than in elder male . And The duration of disease per years affected the level of lipid profile .Finally in the result observed the age of the patient correlates positively with the level of lipid profile .