Assessment of Blood Cell Count in Sudanese Pregnant Women at Third Trimester Attended to Hassahissa and Aboasher Hospitals in Gazera State

Abstract

This was case control study, conducted in Hassahissa Obstetric Hospital and Aboasher Hospitals in Gazera state from February to march 2016, aimed to determine complete blood count (CBC ) in Sudanese pregnant women in third trimester. Hundred fifty (150) healthy pregnant women (case) and Hundred (100) non pregnant women (controls) were informed about the study and agreed for participation. Two and half ml EDTA venous blood was collected and analyzed automatically (Mindary) to measure CBC, the data analyzed using SPSS(version16)computer programm. Age group (21-30) years was most frequent in both pregnant and non pregnant women (65.3%,57%) respectively while age group (≤ 20) years was least frequent in both study subjects (11.4%,9%) respectively. Result showed that level of Hb,HCT,RBCs,MCHC,lymphocyte percentage, mix and platelet were significantly decreased in pregnant women when compared with control group (P.value0.01,0.0.000 0.004,0.000,0.007,0.000,0.012 and 0.000 respectively) while TWBCs ,neutrophil, and PDW increased in their count and showed statistical correlation compared with non-pregnant women(P.value0.005,0.000,0.000 respectively), in contrast to MCV and MPV showed no statistical correlation between study group (p .value 0.14,0.30). There was no significant statistical different between age group of pregnant women and Hb,HCT,RBCs,TWBCs and platelet.p.value of Hb of age groups ≤ 20 and 21-30 (p.value = 0.45)HCT of age groups ≤ 20 and ˃ 30 (p.value =0.24). High level in Hb,HCT,RBCs, MCV,MCH and MCHC in pregnant who taken supplement(e.g Fefol and folic acid ) when compared with those without taken supplement (P.value 0.000, 0.000,0.032,0.047,0.016,0.034 respectively).While TWBCs, lymphocyte nutrophil percentage, mix,platelet MPV and PDW was no significant in pregnant women who taken supplement when compared with those without taken supplement (p.value 0.9,0.2 ,0.8,0.1,0.8,0.9,0.2 respectively ). Regard to history of abortion there was no statistical correlation of Hb ,HCT ,RBCs MCH, MCHC,TWBCs,lymphocyte,neutrophil,mix ,platelet, MPV and PDW in pregnant women with history of abortion when compared to those without history of abortion also there was insignificant increase in level of MCV due to increase production of RBCs to meet the demands of pregnancy. There was no statistical correlation of Hb, HCT, RBCs, MCV,MCH, MCHC,TWBCs, lymphocyte, neutrophil, mix, plateletMPV and PDW of pregnant women who’s attended clinical regularly compared with irregular clinical followup.)p value ≥ 0.05).