Assessment of the plasma levels of Urate and Magnesium in Sudanese Patients with Type 1 diabetes

Abstract

Across-sectional study conducted during the period from March to July 2011, aimed to asses the plasma levels of urate and magnesium in Sudanese with type 1 diabetes. This study includes 75 samples collected from 45 diabetic patients as a test group and 30 apparently healthy (non diabetics) as controls. This study was done in Omdurman hospital. Age and sex of the test group were matched with the control group. The magnesium and urate levels were measured using a spectrophotometer and reagent from Biosystem Company .The data was analyzed using SPSS computer program. The Results showed a significant reduction in the mean of the plasma levels of magnesium of the diabetic group when compared with the control group (p<o.o5). Also showed a significant increase in the mean of the plasma levels of urate of the diabetes group when compared with that of the control group .There is a weak positive correlation between the duration of diabetes and the plasma levels of urate and negative correlation between the duration plasma levels of magnesium, and there is a weak positive correlation between the plasma levels of urate and magnesium. In conclusion: The plasma levels of magnesium are reduced in diabetic patients with type 1 where as that of urate are raised. The plasma levels of magnesium have negative correlation with the duration of diabetes, where as the plasma levels of urate have a positive correlation with the duration of disease.