Study of Contrast-Enhancement in Normal and Pathological Brain Tissue in Magnetic Resonance Image

Abstract

The aim of this study was to determine if a contrast agent provides additional information for characterization of brain lesion and normal tissue. The advantages of magnetic resonance imaging (MRI) over other diagnostic imaging modalities are its higher spatial resolution and its better discrimination of soft tissue. This study of brain diseases relied on quantitative measures obtained from MR scans that are segmented into the three common tissue types present in the human brain: cerebral gray matter (GM), cerebral white matter (WM), and cerebral spinal fluid (CSF). The study was carried out in Antalya Medical Center during the period from July to October and included 63 brain lesion patients. The performance of contrast agent was evaluated by measuring signal intensity and comparing the diagnostic accuracy of MRI image with contrast and without contrast. The results indicate that the same effect of Contrast on Lesion tissue and normal tissue for all ages and for both males and females and the diagnosis doesn’t dependent on age or gender. The results showed the effectiveness of the contras agent and the achieved improvement in image quality. As the contrast agent improves the detection of brain lesion according to the type of lesion, this was clearly shown by the results. Also the results indicate that the ability of contrast-enhanced MRI to identify additional information for characterization of Pathological Brain Tissue and Enhanced the normal tissue according to the type of tissue.