Serum Gondotropins Levels Among Sudanese Men with Infertility

Abstract

Background: Infertility is the inability of a sexually active, non-contracepting couple to achieve pregnancy in one year .the causes for a male infertility include :Congenital factors, Acquired urogenital abnormalities, Urogenital tract infections, Increased scrotal temperature Endocrine disturbances , Systemic diseases. Materials and Methods: In a cross-sectional study population 150 males randomly were enrolled in this study, (75 males as control and 75 males As cases. Semen fluid was collected to measure sperm by (CASA) and serum was collected to measure gonadotropins (FSH, LH) by ELISA technique. Results: In both Azoospermia and oligospermia groups the means concentrations of ( FSH ) was significantly increased compared to control group (18.1 ± 9.1m Iu\mL) (14.4 ± 7.08 m Iu\mL) vs (6.4 ± 7.03 m Iu\mL) with p.value (0.00) (0.00) respectively. Also the means concentrations of (LH) in Oligospermia and Azoospermia groups Was significantly increased compered to control group(14.1± 9.4 m Iu\mL) (11.1 ± 7.1 m Iu\mL) vs (6.4 ± 7.03 m Iu\mL) with p.value (0.02) (0.03) respectively. Conclusion:The study concluded that there is inverse association between serum level of( FSH ,LH ) and low sperm count this could contribute the pathogenesis of male infertility.