A Study of Optical and Thermal Effectsof Gold Nanoparticles

Abstract

The interaction between nanoparticles and radiation holds great interest in Nano medicine. Hyperthermia by laser has been considered as safe cancer treatments methods with lower harmful effects on normal tissues. Using nanoparticles in cancer treatment has improved laser therapy, which is based on a selective cell targeting method to localize cell damages. Metallic nanoparticles such as gold, silver, and copper have been recognized to highly interact with laser beam because of surface plasmon resonance phenomena. i.e. the resonant oscillation of free electrons in the nanoparticles with light. Due to toxicity of silver and copper, gold nanoparti¬cle has received great interest in nanomedicine particularly as a protein denaturizing agent applied to the targeted cells. On the other hand, interaction between laser beam and nanoparti¬cles depends on laser properties, medium and particle characteristics. This project divided into two steps Firstly focused on simulation optical property of Gold nanoparticles to determining the absorption characteristics of the nanoparticle given the medium, particle, and laser parameters .Secondly the nanoparticle temperature over time numerically determined by solving the heat transfer equation using One temperature model , the effects of different Optical and thermal parameters on the Time Dynamics of Nanoparticle Heating were discussed.